How to read a kratom extract certificate of analysis

By Rams Exotics Quality Team · Updated

A useful kratom extract COA names an ISO/IEC 17025 lab, matches the lot number on your packaging, and reports mitragynine, minor alkaloids, 7-OH and MP with detection limits, plus heavy metals, microbiology and residual solvents. A COA missing any of these, or without a lot number, does not describe what you received.

1. Identity: lab, lot and date

  • Laboratory name and accreditation number (ISO/IEC 17025), with the accreditation scope covering the methods used
  • Lot or batch number that matches your drum label
  • Sample receipt and report dates

2. Alkaloid profile

Expect mitragynine plus the main minor alkaloids (speciogynine, paynantheine, speciociliatine), measured by HPLC or LC-MS/MS. Values should be stated as % w/w with the method named.

3. 7-OH and MP

Since October 2026 these are the most important lines on the page. Both should be reported with a limit of quantitation; 'ND' means nothing without the detection limit beside it. Convert to mg/g (0.1% = 1 mg/g) and check the mitragynine ratio.

4. Contaminants

PanelTypical methodWhat to look for
Heavy metals (Pb, As, Cd, Hg)ICP-MSEach metal reported against a stated limit
MicrobiologyPlate count / PCRSalmonella and E. coli absent; TAMC, yeast and mold counts
Residual solventsGC-HSEach extraction solvent reported against a limit

Red flags

  • No lot number, or one COA reused across many lots
  • Alkaloid-only certificate while the seller claims full contaminant testing
  • Lab not named, or COAs available only by email
  • 7-OH shown without units or a detection limit

Related products

Sources

  1. ACS Laboratory: third-party kratom testing
  2. UF Health: kratom products frequently mislabeled (2026)